Radiochemistry/Cyclotron Services

Services

The Radiochemistry and Cyclotron Facility produces radioactive targeting molecules for PET imaging studies. Services offered:

  • We produce a menu of PET tracers which are not commercially available.
  • We perform custom syntheses of novel PET tracers
  • Our on-site cyclotron allows production on demand of PET radionuclides 18F, 11C, and 13N
  • The PET radionuclides 64Cu, 89Zr, and 124I are also available from third party vendors
  • 99mTc SPECT tracers are also available

Radionuclides

The most commonly used PET radionuclides are 18F and 11C, which are produced on site. Longer lived 64Cu, 89Zr, and 124I, available every 1-2 weeks, are better matched to the longer uptake and residence times of higher molecular weight PET probes such as antibodies, peptides, and nanoparticles.

PET RADIONUCLIDE PROPERTIES
Radionuclide Half-Life Decay Mode(s) Availability
18F 110 min β+ Daily on site
11C 20 min β+ Daily on site
13N 10 min β+ Daily on site
64Cu 12.7 h β+, EC, β-, γ Every 2 weeks by supplier
89Zr 78.4 h β+, EC, γ Weekly by supplier
124I 4.2 days β+, EC, γ Weekly by supplier

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