Biomedical Engineering

Departmental Seminar Series: Jason Ortega, Lawrence Livermore National Laboratory

January 14, 2016
4:10 pm to 5:10 pm

Jason Ortega, Ph.D. Senior Scientist Lawrence Livermore National Laboratory

Jason Ortega, Ph.D.
Senior Scientist
Lawrence Livermore National Laboratory

“Virtual Treatment of Basilar Aneurysms Using Shape Memory Polymer Foam”

Numerical simulations are performed on patient-specific basilar aneurysms that are treated with shape memory polymer (SMP) foam embolic devices. To assess the post-treatment hemodynamics, the foam geometry is obtained from a micro-CT scan and the pulsatile blood flow within the treated aneurysm is simulated with a non-Newtonian viscosity model. Virtual angiography and additional post-processing demonstrate that the SMP foam significantly reduces the blood flow speed within the treated aneurysms, while eliminating the high-frequency velocity fluctuations that are present within the pre-treatment aneurysms. Short-term treatment outcomes are assessed by predicting thrombus development using both a low fidelity, correlation-based thrombosis model and a medium fidelity model that incorporates time-dependent coupling of the biofluid and biochemical phenomena. This medium fidelity model yields a more physiologically relevant time history of thrombus growth.

Location
1005 GBSF

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