Research in our laboratory is focused on promoting better diagnosis, treatment and prevention of human diseases through advancements in biophotonics technology – a field at the interface of physical sciences, engineering, biology and medicine. Our research projects target research for development of optical spectroscopy and imaging techniques for medical diagnostics and integration of these techniques in multimodal tissue diagnostic platforms including high-frequency ultrasound technologies. We explore the relationship between tissue pathology and measured optical and ultrasound responses. Many of our studies are conducted in close collaboration with clinical departments (various surgical departments, otolaryngology, cardiology, and pathology). Our work is supported in part by several National Institutes of Health research grants.
|RECENT NEWS & ACHIEVEMENTS
|February 12 2015: Job opening: Post-doctoral position in Marcu laboratory
February 2, 2015 : Two CIRM grants to develop tools for assessing the safety and efficacy of bioengineered tissues used to treat cardiovascular disease and bone and cartilage repair.October 21, 2014: NCI grant to adapt biophotonic technology into a robotic surgical device for head and neck cancer surgery
September 24, 2014 : NCI grant to improve brain cancer surgery using biophotonics.
July 17, 2014: A new book co-edited by Dr. Marcu has been published titled “Fluorescence Lifetime Spectroscopy and Imaging: Principles and Applications in Biomedical Diagnostics” Eds. L. Marcu, P.M.W. French, and D.S. Elson CRC Press Taylor & Francis
|CLEO 2015 Research Conference (10-15 May 2015, San Jose, CA)SPIE Photonics West 2015 (7 – 12 February 2015, San Francisco, CA)
Optics in the Life Sciences (12-15 April 2015, Vancouver, Canada)
Biophotonics Monthly Group Meetings resume October 2014
|H. Fatakdawala et al., “Fluorescence Lifetime Imaging Combined with Conventional Intravascular Ultrasound for Enhanced Assessment of Atherosclerotic Plaques: an Ex Vivo Study in Human Coronary Arteries.” J. Cardiovasc Trans Res 1-11, (2015)
D. Ma et al., “Technique for real-time tissue characterization based on scanning multispectral fluorescence lifetime spectroscopy (ms-TRFS),” Biomed. Opt. Express 6, 987-1002 (2015).Hartl et al. “Characterizing low fluence thresholds for in vitro photodynamic therapy,” Biomed. Opt. Express, (2015)More publications