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Spats
Read Processing and Reactivity Generation for SHAPE-Seq

Spats utilizes a novel statistical inference method to recover RNA structural information from SHAPE-Seq experiments, which multiplex SHAPE probing of multiple RNAs in conjunction with next-generation sequencing.

Papers: Aviran et al., PNAS, 2011Mortimer et al., Curr Protocols in Chem Biol, 2012

 

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