4D Active-MRI

Recent News

4D Active-MRI of the thumb carpometacarpal joint was presented at the 1st International Thumb Osteoarthritis Workshop in Newport, Rhode Island.

Brief description

4D Active-MRI of the thumb carpometacarpal joint; the black and white images show snapshots during thumb flexion-extension, while the color images are snapshots from 4D renderings generated from the 4D active-MR images during thumb adduction-abduction.

Our research group is has recently optimized an active-MRI protocol to produce 4D (X, Y, Z and time) images of the joints of the hand. We are embarking on a study to measure kinematic differences between healthy men and women from 4D active-MRI and evaluate whether differences in biomechanics based on sex may explain why conditions such as hand osteoarthritis disproportionately affect women.

Research team

Abhijit J. Chaudhari, Ph.D., Robert D. Boutin, M.D., Michael H. Buonocore, M.D., Ph.D., Robert J. Szabo, M.D., M.P.H., Ramsey D. Badawi, Ph.D., Nancy E. Lane, M.D., Kwan-Liu Ma, Ph.D.

Research Support

National Institutes of Health (NIH) grants K12 HD051958 and R03 EB015099 to Chaudhari and  pilot grants from the UC Davis Imaging Research Center to Chaudhari and Buonocore.

Relevant publications

A. J. Chaudhari, A. A. Joshi, R. M. Leahy, B. L. Wise, N. E. Lane, R. D. Badawi, R. D. Boutin and M. H. Buonocore, Thumb carpometacarpal joint motion and bone shape differences by sex, Proceedings of the 1st International Thumb Osteoarthritis Workshop, Newport, Rhode Island, USA October 25-26, 2013

Interested in knowing more

Please contact Dr Chaudhari at ajchaudhari AT ucdavis DOT edu


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