Carpal bone shape analysis

Recent News

Article on the application of Global Point Signature to carpal bone shape analysis is accepted for publication by the journal Physics in Medicine and Biology.

Brief description

Global point signature-based basis functions rendered on the first metacarpal for analysis of shape

Our research group is investigating techniques to quantify carpal bone shape. The goals are two fold: (1) to allow a comparison across populations based on sex, age and other factors, in the context of musculoskeletal disease, and (2) to allow the measurement of changes in bone shape in conditions where such changes may occur because of the disease process or due to intervention, such as in Rheumatoid Arthritis.

Research team

Abhijit J. Chaudhari, Ph.D., Anand A. Joshi, Ph.D., Richard M. Leahy, Ph. D., Ramsey D. Badawi, Ph.D., Nancy E. Lane, M.D., Barton L. Wise, M.D., Kwan-Liu Ma, Ph.D.

Research Support

National Institutes of Health (NIH) grants K12 HD051958 and R03 EB015099 to Chaudhari.

Relevant publications

A. J. Chaudhari, R. M. Leahy, B. L. Wise, N. E. Lane, R. D. Badawi, and A. A. Joshi, Global point signature for shape analysis of carpal bones. Physics in Medicine and Biology. 2014; 59(4):961-973

A. A. Joshi, R. M. Leahy, R. D. Badawi and A. J. Chaudhari, Morphometry for early monitoring of treatment response in Rheumatoid Arthritis, Proc. IEEE International Symposium on Biomedical Imaging (2013)

Interested in knowing more

Please contact Dr Chaudhari at ajchaudhari AT ucdavis DOT edu


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