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Welcome to the George Laboratory

 

Transport and Tissue Engineering

 
We have openings for one or more doctoral-level researchers in the areas of microfabrication, stem cell technology and organ-on-a-chip technologies‚Äč. More information please contact Dr. George by email (scgeorge@ucdavis.edu).  3-29-18

Steven C George, MD, PhD

Our research program is focused in three broad areas of transport phenomena, tissue engineering, and “organ-on-a-chip” technologies which include: 1) 3D microphysiological systems to simulate vascularized cardiac, tumor, and pancreatic tissue; 2) 3D microphysiological systems of the tumor microenvironment to probe mechanisms of metastasis including collective migration, intravasation, and extravasation; and 3) tissue engineered models of cardiac and vascular development.

We utilize both experimental and theoretical techniques. The projects are multidisciplinary and involve active collaborations at UCI with Professors Chris Hughes, Abe Lee, Leslie Lock, and Marian Waterman. In addition, we collaborate with Professor Karen Christman and Maike Sander at UCSD and Dr. Bruce Conklin at the Gladstone Institute in the Bay area.  Newer collaborations at Washington University include Professors Greg Longmore, Stacey Rentschler, Rebecca Aft, Cynthia Ma, and Ryan Fields.  The tissue engineering projects are supported by a fully-equipped modern cell and tissue culture lab, and actively employ modern stem biology techniques (e.g., differentiation of induced pluripotent stem cells), fabrication of microfluidic devices using soft lithography, and non-invasive (optical) assessment or characterization of oxygen tension using phosphorescent lifetime imaging (PhLIM).  We invite you to explore the lab in more details including specific research projects and the quality individuals that make up the lab.

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