Welcome to

Marcu Laboratory


Optical Spectroscopy and Ultrasound for disease diagnosis


Research in our laboratory is focused on promoting better diagnosis, treatment and prevention of human diseases through advancements in biophotonics technology – a field at the interface of physical sciences, engineering, biology and medicine. Our research projects target research for development of optical spectroscopy and imaging techniques for medical diagnostics and integration of these techniques in multimodal tissue diagnostic platforms including high-frequency ultrasound technologies. We explore the relationship between tissue pathology and measured optical and ultrasound responses. Many of our studies are conducted in close collaboration with clinical departments (various surgical departments, otolaryngology, cardiology, and pathology). Our work is supported in part by several National Institutes of Health research grants.

Our research focus can also be seen in a book co-edited by Dr. Marcu has been published titled “Fluorescence Lifetime Spectroscopy and Imaging: Principles and Applications in Biomedical Diagnostics.”


Congratulations to Ben, Jen, Julien and Laura for their new publication in The Optical Society (OSA). The paper present a novel fiber-based imaging platform that allows simultaneous fluorescence lifetime imaging (FLIm) and optical coherence tomography (OCT) using a double-clad fiber. Read more

Stayed tuned for seminars and workshops coming up after the summer break! B.A. Hartl et al., “The effect of radiation dose on the onset and progression of radiation-induced brain necrosis in the rat model”, Int. J. Rad. Biol. (2017)


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