Welcome to

Marcu Laboratory


Optical Spectroscopy and Ultrasound for disease diagnosis


Research in our laboratory is focused on promoting better diagnosis, treatment and prevention of human diseases through advancements in biophotonics technology – a field at the interface of physical sciences, engineering, biology and medicine. Our research projects target research for development of optical spectroscopy and imaging techniques for medical diagnostics and integration of these techniques in multimodal tissue diagnostic platforms including high-frequency ultrasound technologies. We explore the relationship between tissue pathology and measured optical and ultrasound responses. Many of our studies are conducted in close collaboration with clinical departments (various surgical departments, otolaryngology, cardiology, and pathology). Our work is supported in part by several National Institutes of Health research grants.

Our research focus can also be seen in a book co-edited by Dr. Marcu has been published titled “Fluorescence Lifetime Spectroscopy and Imaging: Principles and Applications in Biomedical Diagnostics.”

Dr. Laura Marcu writes about how she uses fluoresence lifetime imaging microscopy to help surgeons delineate the margins of tumors. Read article …

Project Highlights – Photonics Media Light Matters Extra: Taking Photonics Innovations from the Lab to the Operating Room … Full video clips



01/25  5pm: Prof. Jane Brock, Harvard Medical School, Challenges and Innovative Approaches for the Diagnosis of Breast Cancer in Low and Middle Income Countries

12/06 4pm: Prof. Harrison Barrett, University of Arizona, New Directions in Biomedical Imaging and Precision Cancer Therapy


Upcoming seminars and workshops.

Unger, J, Sun, T, Chen, YL, Phipps JE, Bold, RJ, Darrow, MA, Ma, KL and Marcu, L, “Method for accurate registration of tissue autofluoresence imaging data with corresponding histology: a means for enhanced tumor margin assessment”, Journal of biomedical optics.



Comments are closed.