Faculty Content https://bme.ucdavis.edu/directory/faculty Faculty Content for Biomedical Engineering en Steven C. George https://bme.ucdavis.edu/people/steven-george <h5>"Organ-on-a-chip," pluripotent stem cells, tissue engineering, microfluidics</h5> <p><a href="https://georgelab.bme.ucdavis.edu/">The George Lab</a> uses stem cell, microfluidic and computational technologies to develop 3D mimics of human organs, known as "organs-on-a-chip." The lab specifically focuses on cancer (pancreatic, colorectal and breast), the cardiovascular system (perfused microcirculation, cariomyocytes) and the pancreas. Applications include enhanced understanding of biologic mechanism and drug discovery for diseases such as atrial fibrillation and Type-1 diabetes.</p> November 19, 2018 - 4:49pm Noah A Pflueger-Peters https://bme.ucdavis.edu/people/steven-george Soichiro Yamada https://bme.ucdavis.edu/people/soichiro-yamada <h5>Mechano-biology, cell migration and adhesion, cytoskeleton, cancer </h5> <p>Dr. Yamada is interested in how mammalian cells touch, feel and work together to form multi-cellular tissues and organs. <a href="https://yamadalab.ucdavis.edu/">The Yamada Group</a> focuses on the mechanisms by which physical forces regulate protein and cell interactions, and therefore, collective cell behaviors. Since abnormal cell adhesion is common in diseases like cancer, understanding cell adhesion regulation should lead to insights for cancer therapy.</p> November 21, 2018 - 1:36pm Noah A Pflueger-Peters https://bme.ucdavis.edu/people/soichiro-yamada Aijun Wang https://bme.ucdavis.edu/people/aijun-wang <h5>Stem cells, biomaterials, tissue regeneration, vascular disease, birth defects </h5> <p>Dr. November 21, 2018 - 1:12pm Noah A Pflueger-Peters https://bme.ucdavis.edu/people/aijun-wang Leonor Saiz https://bme.ucdavis.edu/people/leonor-saiz <h5>Systems therapeutics, computational biomedicine, biological networks, biomolecular systems, bioinformatics </h5> <p>Dr. Saiz’s <a href="https://saizlab.bme.ucdavis.edu">Modeling of Biological Networks and Systems Theraputics Laboratory</a> develops and applies computational approaches to characterize the properties of protein-protein and protein-DNA complexes and their effects on cellular processes. Her lab’s current projects include studying molecular dynamics on the atomic scale and applying network methods to investigate mammalian gene regulation and signal transduction. November 21, 2018 - 11:47am Noah A Pflueger-Peters https://bme.ucdavis.edu/people/leonor-saiz Volkmar Heinrich https://bme.ucdavis.edu/people/volkmar-heinrich <h5>Cellular and molecular biophysics, immune cell behavior, single-molecule interactions </h5> <p>Dr. November 21, 2018 - 11:38am Noah A Pflueger-Peters https://bme.ucdavis.edu/people/volkmar-heinrich Yong Duan https://bme.ucdavis.edu/people/yong-duan <h5>Design and construction of synthetic biomolecular networks, protein and RNA engineering, directed evolution, biosensors </h5> <p>Dr. Duan is interested in the development and application of computational methods to study the structure and dynamics of bio-molecular systems. November 21, 2018 - 11:23am Noah A Pflueger-Peters https://bme.ucdavis.edu/people/yong-duan John M. Boone https://bme.ucdavis.edu/people/john-boone <h5>Breast imaging, computed tomography, radiation dose assessment, image quality evaluation </h5> <p>Dr. Boone researches the design, fabrication and testing of breast imaging systems using cone beam computed tomography (CT). <a href="https://boonelab.bme.ucdavis.edu/">The Boone Lab</a> has developed four breast CT scanners that have imaged over 600 women in the last 18 years. Boone’s group was the first to use cone beam dedicated breast CT in humans and in collaboration with Drs. Cherry and Badawi, they were able to integrate PET imaging into two of the four scanners. November 21, 2018 - 11:13am Noah A Pflueger-Peters https://bme.ucdavis.edu/people/john-boone Craig J. Benham https://bme.ucdavis.edu/people/craig-benham <p><a href="https://benham.bme.ucdavis.edu/">Dr. Benham’s research group</a> develops statistical mechanical methods to computationally analyze structural transitions in stressed DNA molecules. These methods have been used to analyze a wide variety of genomic DNA sequences, including the complete genomes of Escherichia coli, Saccharomyces cerevisciae, and Homo sapiens. The group has shown that the susceptibility to stress-induced destabilization is closely associated with several types of DNA regulatory regions. November 21, 2018 - 10:43am Noah A Pflueger-Peters https://bme.ucdavis.edu/people/craig-benham Julie Sutcliffe https://bme.ucdavis.edu/people/julie-sutcliffe <h5>Translational Molecular Imaging, probe development and screening. </h5> <p>Dr. November 21, 2018 - 10:38am Noah A Pflueger-Peters https://bme.ucdavis.edu/people/julie-sutcliffe Sanjeevi Sivasankar https://bme.ucdavis.edu/people/sanjeevi-sivasankar <h5>Molecular and cellular mechanobiology, single molecule biophysics, instrument development </h5> <p>Dr. Sivasankar aims to resolve the physical principles by which cells sense and respond to mechanical stimuli. <a href="https://sivasankarlab.ucdavis.edu">The Sivasankar Group</a> focuses two research themes: the biophysical studies of mechanical tension sensing in cells and bioengineering tool development. The group’s projects include biophysical studies of cell-cell adhesion and its regulation and the development of high resolution techniques to quantify the effect of mechanical force on p November 21, 2018 - 10:28am Noah A Pflueger-Peters https://bme.ucdavis.edu/people/sanjeevi-sivasankar