A new study published by Kent Leach's group at UC Davis shows that mesenchymal stem cells (MSCs) can adapt to their environment and become resistant to low oxygen to carry out their function.
First, a replica of your heart that a doctor can hold in her hands. Next, a living sensor inside your phone that detects nearby pollutants or pathogens. That’s TEAMwork. Their motto is “What can we help you make?”
The Silva Lab is developing a new alginate hydrogel that incorporates chitosan to control the release of S1P to improve the formation of new blood vessels.
Jennifer Choi received a Committee on Research Large Grant for her project titled, “Shedding light on undergraduates’ unsatisfactory problem solving performance in STEM: The role of knowledge structure, knowledge retention, and misconceptions.” Dr. Choi will be collaborating on the project with Ozcan Gulacar (Chemistry) and Marina Crowder (Molecular and Cellular Biology).
Katherine Ferrara has received a 5-year NIH R01 for her project, “Image-guided ultrasound therapy and drug delivery in pancreatic cancer.”
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive and invasive cancer, with a median survival of 6 months and a 5-year survival rate of 6%. Although recent advances have been made in the understanding of PDAC development, effective therapies are lacking.
UC Davis physician Gary Raff was treating a 19-month-old with a congenital heart defect this January when he realized he had reached a rare crossroads – he wasn’t sure what to do next. The girl had a complex constellation of arteries coming off her heart and only 1 1/4 ventricles rather than the usual two.
When UC Davis Pediatric Heart Center surgeons faced a complex patient case in January, they consulted with cardiologists, pediatric intensive care unit physicians, radiologists, and, for the first time, biomedical engineers.
The engineers added a new technology to the clinical care toolkit: a three-dimensional printer that could be used to create a model of the patient’s complex heart anatomy.
Cover image by James C. S. Ho and Atul N. Parikh. Giant lipid vesicles, topologically closed flexible compartments, subject to solute concentration gradients dissipate the available chemical energy through the osmotic movement of water, producing shape transformations driven by surface-area–volume changes.