Publications

UC Davis Researchers Strengthen Stem-Cell Transplants for Better Patient Outcomes

New cell-combination strategy creates longer transplant viability

UC Davis researchers have discovered a promising new way to use a combination of two types of stem cells to improve transplantation viability – and possible patient outcomes.

As outlined in Stem Cell Research & Therapy, the UC Davis team took on a long-standing challenge for stem-cell researchers: stem cells’ potentially short transplant lives.

Engineering new cell-based strategies with microangiospheres

Pre-vascular microtissues delivered in a microhydrogel injection are better able to lay the groundwork necessary for blood vessels to grow. Cell-based strategies are seen as true game changers in the context of ischemic vascular diseases because they aim to cure and not simply to ameliorate these diseases.

NIH funds project to model atrial fibrillation with heart-on-a-chip

George and his collaborators plan to create atrial tissue from a patient’s own stem cells, and induce changes in the cells using CRISPR technology (“gene editing”) to alter their protein expression so that they conduct electricity in a pattern resembling that seen in atrial fibrillation.