Publications

Discovering Typhoid Fever’s Dirty Little Secret

The Centers for Disease Control estimate that typhoid fever affects 21.5 million people around the world each year, and the World Health Organization estimates it causes at least 600,000 deaths. Caused by the Salmonella Typhi bacterium, ingested in food or drink contaminated by the urine or feces of infected people, it is uncommon in regions with adequate sanitation and clean water. However, there are also around 7,500 cases in the United States annually. Globally, it remains a major health problem because it is difficult to eradicate.

Emergent behavior lets bubbles ‘sense’ environment

Tiny, soapy bubbles can reorganize their membranes to let material flow in and out in response to the surrounding environment, according to new work carried out in an international collaboration by biomedical engineers at the University of California, Davis, and Nanyang Technological University in Singapore. This behavior could be exploited in creating microbubbles that deliver drugs or other payloads inside the body — and could help us understand how the very first living cells on Earth might have survived billions of years ago.

Laura Marcu Edits New Book on Fluorescence Lifetime Spectroscopy

Laura Marcu is a co-editor of a new textbook: “Fluorescence Lifetime Spectroscopy and Imaging”. This is the first book providing a comprehensive review of time-resolved (lifetime) fluorescence techniques and their role in a wide range of biological and clinical applications.

Ferrara Lab Paper and Student Win Awards

Katherine Ferrara is the senior author of a paper that has won the Jorge Heller JCR Outstanding Paper Award from the Controlled Release Society. Another Ferrara Lab member, Andrew Wong, received the Nadine Barrie Smith Award from the International Society of Therapeutic Ultrasound in April for his presentation in Las Vegas.

A Rouge Mirror Test for Individual Cells

A new paper by Soichiro Yamada, a professor of biomedical engineering at UC Davis, addresses a simple question, “What happens when single epithelial cells contact their own membrane versus the membrane of neighboring cells?”

Proton Pump Mechanism Discovery Will Aid Optogenetics

A hawk circles lazily in the morning sky outside the window of biomedical engineering Professor Marc Facciotti’s office, overlooking a scenic, tree-covered part of the UC Davis campus. It’s cozy and warm with natural sunlight, which seems appropriate because we’re talking about opsins, light sensitive proteins. You are probably most familiar with the opsin – called rhodopsin – that serves as a photoreceptor in your eyes.