Publications

Tan Lab Develops Tool for Tuning Cellular Noise

June 22, 2020
Cells are noisy entities. This noise manifests through the heterogeneity of protein synthesis and cellular behavior. Understanding and controlling the noise is paramount to various biomedical applications, including drug treatment, tissue engineering, and the design of synthetic cells.

Look What’s Inside: Full-Body Movies From EXPLORER Scanner

January 21, 2020

Positron emission tomography, or PET scanning, a technique for tracing metabolic processes in the body, has been widely applied in clinical diagnosis and research spanning physiology, biochemistry and pharmacology. Now researchers at the University of California, Davis, and Fudan University, Shanghai, have shown how to use an advanced reconstruction method with an ultrasensitive total-body PET scanner to capture real-time videos of blood flow and heart function. The work paves the way for looking at the function of multiple organs, such as the brain and heart, at the same time.

Undergraduate Researchers Make Surprising Discovery in Mechanotransduction Research

October 02, 2019
Undergraduate researchers in the Yamada Lab discovered that when force is applied to a cell, a protein called cten is recruited to these fibrous structures. Since actin was long believed to be an important part of mechanotransduction, the UC Davis researchers inhibited actin to simply show that cten recruitment required actin. To their surprise, the mechano-sensitive response of cten was still present.

UC Davis Researchers Strengthen Stem-Cell Transplants for Better Patient Outcomes

January 30, 2019

New cell-combination strategy creates longer transplant viability

UC Davis researchers have discovered a promising new way to use a combination of two types of stem cells to improve transplantation viability – and possible patient outcomes.

As outlined in Stem Cell Research & Therapy, the UC Davis team took on a long-standing challenge for stem-cell researchers: stem cells’ potentially short transplant lives.

Building tiny bacteria-fighters from the bottom up

August 31, 2018
Faculty, researchers and students at the UC Davis Biomedical Engineering Department’s Tan Lab report they’ve successfully created bacteria-killing artificial cells that operate even in the poorest environments.