Building tiny bacteria-fighters from the bottom up

August 31, 2018
Faculty, researchers and students at the UC Davis Biomedical Engineering Department’s Tan Lab report they’ve successfully created bacteria-killing artificial cells that operate even in the poorest environments.

Engineering new cell-based strategies with microangiospheres

November 06, 2017
Pre-vascular microtissues delivered in a microhydrogel injection are better able to lay the groundwork necessary for blood vessels to grow. Cell-based strategies are seen as true game changers in the context of ischemic vascular diseases because they aim to cure and not simply to ameliorate these diseases.

NIH funds project to model atrial fibrillation with heart-on-a-chip

August 08, 2017
George and his collaborators plan to create atrial tissue from a patient’s own stem cells, and induce changes in the cells using CRISPR technology (“gene editing”) to alter their protein expression so that they conduct electricity in a pattern resembling that seen in atrial fibrillation.

Paralyzed rats walk again after experimental treatment

August 03, 2017
Karen Moxon, a professor of biomedical and mechanical engineering at UC Davis, showed that a combined therapeutic regimen of drugs and physical therapy promoted cortical reorganization that bypassed a spinal cord injury, allowing paralyzed rats to walk again.

Cartilage Responds Positively to Tension: Nature Materials Paper by the Athanasiou Group

June 12, 2017

Scientists have known for 2,300 years that articular cartilage neither repairs itself nor regenerates with ease. “Cartilage, when once cut off, [does not] grow again,” observed Aristotle, the Greek philosopher and scientist, in the fourth century BC.  In the last fifty years, scientists have succeeded in creating tissue that closely resembles native cartilage, but the engineered tissue lacks the tensile values required to endure the natural strains it would encounter when implanted in human joints to replace damaged cartilage.